abstract：:Escherichia coli (E. coli) is a common pathogen in epididymitis, which represents a prevalent entity in male reproductive tract infections (RTI). Although current treatment regimens using antibiotics are satisfactory, development of antimicrobial resistance by the pathogen represents a challenge in the management of R...

journal_title：Andrology

authors： Biswas B,Bhushan S,Rajesh A,Suraj SK,Lu Y,Meinhardt A,Yenugu S

更新日期：2015-03-01 00:00:00

abstract：:Genomic and protein-coding transcriptomic data have suggested that germ cell tumours (GCTs) of childhood are biologically distinct from those of adulthood. Global messenger RNA profiles segregate malignant GCTs primarily by histology, but then also by age, with numerous transcripts showing age-related differential exp...

journal_title：Andrology

authors： Murray MJ,Nicholson JC,Coleman N

更新日期：2015-01-01 00:00:00

abstract：:Defects in bone regulatory pathways have been linked to chronic diseases including cardiovascular disease and cancer. In men, a link between bone metabolism and gonadal hormones has been suggested. However, to date, there is lack of evidence on the association between serum inorganic phosphate (Pi) and sex steroid hor...

journal_title：Andrology

authors： Wulaningsih W,Van Hemelrijck M,Michaelsson K,Kanarek N,Nelson WG,Ix JH,Platz EA,Rohrmann S

更新日期：2014-11-01 00:00:00

abstract：:Prevalence and risk factors of concomitant primary low sexual desire/interest (LSD/I) and subsequent new-onset erectile dysfunction (ED) in men have been only partially investigated. We looked at the sociodemographic and clinical predictors of the concomitant condition of primary LSD/I - defined as the reduction in th...

journal_title：Andrology

authors： Salonia A,Clementi MC,Ventimiglia E,Colicchia M,Capogrosso P,Castiglione F,Castagna G,Boeri L,Suardi N,Cantiello F,Damiano R,Montorsi F

更新日期：2014-09-01 00:00:00

abstract：:Smoking is strongly associated with abnormalities in histone-to-protamine transition and with alteration of protamine expression in human spermatozoa. A proper protamine to histone ratio is, however, essential for sperm chromatin maturity and DNA integrity. Alterations in these sperm nuclear proteins were observed in ...

journal_title：Andrology

authors： Hamad MF,Shelko N,Kartarius S,Montenarh M,Hammadeh ME

更新日期：2014-09-01 00:00:00

abstract：:The molecular basis of spermatogenic failure (SpF) is still largely unknown. Accumulating evidence suggests that a series of specific events such as meiosis, are determined at the early stage of spermatogenesis. This study aims to assess the expression profile of pre-meiotic genes of infertile testicular biopsies that...

journal_title：Andrology

authors： Bonache S,Algaba F,Franco E,Bassas L,Larriba S

更新日期：2014-07-01 00:00:00

abstract：:Erectile dysfunction (ED) is very prevalent in the older population, although the ageing-related mechanisms involved in the development of ED are poorly understood. We propose that age-induced differences in nerve- and endothelium-mediated smooth muscle contractility in the corpus cavernosum (CC) could be found betwee...

journal_title：Andrology

authors： Lafuente-Sanchis A,Triguero D,Garcia-Pascual A

更新日期：2014-07-01 00:00:00

abstract：:In recent reports, an association between altered TRPC channel function and the development of various diabetic complications has drawn the attention of many investigators. The aim of this study was to investigate the expression of TRPC4 channels of corpus smooth muscle (CSM) cells in diabetes, and to evaluate the ass...

journal_title：Andrology

authors： Sung HH,Choo SH,Ko M,Kang SJ,Chae MR,Kam SC,Han DH,So I,Lee SW

更新日期：2014-07-01 00:00:00

abstract：:Brain dysfunction in erectile dysfunction (ED) has been identified by multiple neuroimaging studies. A recent MRI study indicated grey matter alterations in ED patients. This study aims to investigate the microstructural changes of cerebral white matter (WM) in psychological ED patients and their possible correlations...

journal_title：Andrology

authors： Zhang P,Liu J,Li G,Pan J,Li Z,Liu Q,Qin W,Dong M,Sun J,Huang X,Wu T,Chang D

更新日期：2014-05-01 00:00:00

abstract：:Spermatogenesis involves the aggregated action of up to 2300 genes, any of which, could, potentially, provide targets for diagnostic tests of male factor infertility. Contrary to the previously proposed common variant hypothesis for common diseases such as male infertility, genome-wide association studies and targeted...

journal_title：Andrology

authors： Hotaling J,Carrell DT

更新日期：2014-05-01 00:00:00

abstract：:Zona pellucida-based induction of acrosome reaction (AR) is a popular and well-accepted hypothesis. However, this hypothesis is being challenged in recent years and it has been proposed that the cumulus cells might be the site of AR. In our previous study, we reported the presence of a synaptic protein Liprin α3 on sp...

journal_title：Andrology

authors： Joshi CS,Khan SA,Khole VV

更新日期：2014-03-01 00:00:00

abstract：:Treatment of testicular cancer includes the coadministration of bleomycin, etoposide and cis-platinum (BEP); however, along with its therapeutic benefit, BEP exposure results in extensive reproductive chemotoxic effects, including alterations to sperm chromatin integrity. As an intact paternal genome is essential for ...

journal_title：Andrology

authors： Maselli J,Hales BF,Robaire B

更新日期：2014-03-01 00:00:00

abstract：:Maternal overweight and obesity in pregnancy has been associated with earlier age of menarche in daughters as well as reduced semen quality in sons. We aimed at investigating pubertal development in sons born by mothers with a high body mass index (BMI). The study included 2522 sons of mothers that during pregnancy in...

journal_title：Andrology

authors： Hounsgaard ML,Håkonsen LB,Vested A,Thulstrup AM,Olsen J,Bonde JP,Nohr EA,Ramlau-Hansen CH

更新日期：2014-03-01 00:00:00

abstract：:The main aim of this work was to evaluate how supplementing freezing media with reduced glutathione (GSH) affected the 'in vivo' fertilizing ability of boar semen subjected to cryopreservation procedures. With this purpose, 12 ejaculates coming from 12 boars were cryopreserved in the presence or absence of 2 mm GSH, w...

journal_title：Andrology

authors： Estrada E,Rodríguez-Gil JE,Rocha LG,Balasch S,Bonet S,Yeste M

更新日期：2014-01-01 00:00:00

abstract：:The published incidence of bilateral varicocoeles in adults is much higher than among adolescents. We investigated our adolescent varicocoele database to determine (i) the presence of subclinical and palpable right varicocoele s in boys with a left varicocoele, (ii) the effect, if any, of right varicocoele on asymmetr...

journal_title：Andrology

authors： Woldu S,Nees S,Van Batavia J,Spencer B,Glassberg K

更新日期：2013-11-01 00:00:00

abstract：:To analyze the pathogenesis of persistent and refractory haematospermia and to evaluate the aetiological diagnostic value of magnetic resonance imaging (MRI) for this type of haematospermia. Clinical data from 102 patients with persistent and refractory haematospermia was retrospectively analysed. Data collected inclu...

journal_title：Andrology

authors： Li BJ,Zhang C,Li K,Zhang J,Zhang Y,Sun ZY,Kang HY,Zhou B,Jin FS,Zhang KQ,Li YF

更新日期：2013-11-01 00:00:00

abstract：:Scarce data are available on epidemiology of varicocoele, the most common surgically correctable cause of male infertility. The objectives of this study were to evaluate the association between body mass index (BMI) and varicocoele and to assess trends in prevalence over time. We conducted a nationwide population-base...

journal_title：Andrology

authors： Rais A,Zarka S,Derazne E,Tzur D,Calderon-Margalit R,Davidovitch N,Afek A,Carel R,Levine H

更新日期：2013-09-01 00:00:00

abstract：:Growth hormone (GH) and insulin-like growth factor I (IGF-I) receptors are present on pituitary gonadotrophs and on testicular Leydig and Sertoli cells. Thus, the GH/IGF-I system may modulate the pituitary-gonadal axis in males. This is a randomized cross-over study. Eight healthy male volunteers (mean age 35, range 2...

journal_title：Andrology

authors： Andreassen M,Frystyk J,Faber J,Kristensen LØ,Juul A

更新日期：2013-07-01 00:00:00

abstract：:Research in the last decade has revealed that bone is not only a target tissue for numerous circulating hormones but functions as an endocrine organ itself. As a recent study demonstrated a stimulatory effect of the osteoblast-derived hormone osteocalcin (OCN) on testosterone production in mice, we investigated whethe...

journal_title：Andrology

authors： Hannemann A,Breer S,Wallaschofski H,Nauck M,Baumeister SE,Barvencik F,Amling M,Schinke T,Haring R,Keller J

更新日期：2013-05-01 00:00:00

abstract：:The aetiology of severe asthenozoospermia in men with spinal cord injury includes an adverse impact of seminal plasma (SP) on sperm motility. In this study we investigated the effect exerted by SP from men with SCI on donor sperm mitochondrial activity and its reflection on motility. Donor spermatozoa were exposed (1 ...

journal_title：Andrology

authors： Barbonetti A,Vassallo MR,Di Rosa A,Leombruni Y,Felzani G,Gandini L,Lenzi A,Necozione S,Francavilla S,Francavilla F

更新日期：2013-05-01 00:00:00

abstract：:Spermiogenesis is the final phase of spermatogenesis. During this process, haploid round spermatids differentiate into spermatozoa, with dramatic morphological changes, including elongation and condensation of the nuclei, and formation of the flagella. Meig1 is one of many genes involved in the regulation of this proc...

journal_title：Andrology

authors： Shi Y,Zhang L,Song S,Teves ME,Li H,Wang Z,Hess RA,Jiang G,Zhang Z

更新日期：2013-05-01 00:00:00

abstract：:Erectile dysfunction (ED) is increasingly recognized as a public health problem. Several studies have reported the influence of the insertion/deletion (I/D) polymorphism in the Angiotensin-converting enzyme (ACE) gene on ED susceptibility, but the results remain controversial. To derive a more precise estimation of th...

journal_title：Andrology

authors： Zhang T,Li WL,He XF,Wu ZY,Liu LH,He SH,Wei AY

更新日期：2013-03-01 00:00:00

abstract：:To add new arguments concerning the origin of the sperm-head vacuoles observed under high magnification with interference contrast microscopy, we carried out in two patients with total globozoospermia confirmed using transmission electron microscopy (TEM), a detailed sperm morphometric analysis with high magnification...

journal_title：Andrology

authors： Gatimel N,Léandri RD,Foliguet B,Bujan L,Parinaud J

更新日期：2013-01-01 00:00:00

abstract：:The medical treatment is indicated in the development stage of Peyronie's disease (PD) for at least 1 year after diagnosis and whenever in case of penile pain. This research was conducted to demonstrate the possible effectiveness of vitamin E in PD treatment, whereas in the scientific literature this topic is much dis...

journal_title：Andrology

authors： Paulis G,Brancato T,D'Ascenzo R,De Giorgio G,Nupieri P,Orsolini G,Alvaro R

更新日期：2013-01-01 00:00:00